Trilavir D Tablet

Description

Generic Name:

Lamivudine + Zidovudine + Nevirapine

 

Composition:

Each Trilavir D Tablet contains:

• Lamivudine (150mg): A nucleoside reverse transcriptase inhibitor (NRTI) that prevents the replication of the HIV virus by blocking viral DNA synthesis.
• Zidovudine (300mg): Another NRTI that inhibits the HIV enzyme reverse transcriptase, reducing viral replication.
• Nevirapine (200mg): A non-nucleoside reverse transcriptase inhibitor (NNRTI) that prevents HIV from multiplying in the body.
• Excipients: Microcrystalline cellulose, magnesium stearate, povidone, and lactose monohydrate (inactive ingredients that support tablet stability and absorption).

 

Indication:

Trilavir D Tablet is indicated for the management and treatment of:

• Human Immunodeficiency Virus (HIV-1) infection in adults and adolescents.
• Reduction of viral load to help improve immune function.
• Prevention of mother-to-child transmission of HIV during pregnancy when used as part of antiretroviral therapy (ART).

 

Storage Instructions:

• Store at room temperature (15-30°C) in a cool, dry place.
• Keep away from direct sunlight, heat, and moisture.
• Keep out of reach of children and pets.
• Do not store in humid environments like bathrooms.
• Properly dispose of expired or unused medication as per local disposal regulations.

 

Uses of the Medicine:

Trilavir D Tablet is used for:

• Treatment of HIV infection to suppress viral load and slow disease progression.
• Combination therapy in ART regimens for effective HIV management.
• Prevention of opportunistic infections by maintaining a strong immune system.

 

Benefits of the Medicine:

• Reduces HIV viral load and prevents disease progression.
• Improves immune function by increasing CD4 cell counts.
• Reduces the risk of HIV-related complications and co-infections such as tuberculosis and pneumonia.
• Prevents transmission of HIV from mother to child when used correctly during pregnancy.

 

Side Effects:

Common side effects may include:

• Gastrointestinal Issues: Nausea, vomiting, diarrhea, or bloating.
• Neurological Effects: Dizziness, headache, or fatigue.
• Skin Reactions: Rash, itching, or mild hypersensitivity.
• Muscle and Joint Pain: Common during the first few weeks of treatment.

 

Serious Side Effects Include:

Seek immediate medical attention if you experience:

• Severe Allergic Reactions: Swelling of the face, lips, or throat; difficulty breathing.
• Lactic Acidosis: Unusual weakness, muscle pain, rapid breathing, nausea, or irregular heartbeat.
• Liver Toxicity: Yellowing of skin/eyes, dark urine, severe stomach pain.
• Bone Marrow Suppression: Low blood cell counts, leading to infections or anemia.
• Stevens-Johnson Syndrome (SJS): Severe skin reactions, blistering, or peeling.

 

How to Use the Medicine:

• Take one tablet twice daily or as prescribed by your doctor.
• Swallow the tablet whole with a glass of water.
• Can be taken with or without food.
• Do not skip doses to avoid resistance.
• If you experience nausea, take it with a light meal to reduce discomfort.

 

How the Medicine Works:

Trilavir D Tablet contains three active ingredients that work together to suppress HIV:

• Lamivudine & Zidovudine: Block the HIV enzyme reverse transcriptase, preventing the virus from replicating.
• Nevirapine: Binds to the enzyme, disrupting its function and stopping viral multiplication.

 

What If You Forget to Take the Medicine?

• Take the missed dose as soon as possible.
• Skip the missed dose if it is close to the next scheduled dose.
• Do not take a double dose to make up for a missed one, as this may increase the risk of side effects.

 

Quick Tips:

• Take your medication at the same time every day to maintain effectiveness.
• Stay hydrated and follow a balanced diet to support immune function.
• Avoid alcohol consumption, as it may increase the risk of liver toxicity.
• Inform your doctor if you develop any unusual symptoms.
• Regularly monitor your CD4 count and viral load to track treatment progress.

 

 

Safety Advice

 

Caution is advised when consuming alcohol with Trilavir D Tablet. Please consult your doctor for guidance.

 

Trilavir D Tablet is unsafe to use during pregnancy due to potential harm to the developing baby. It may only be prescribed in life-threatening situations where benefits outweigh the risks. Please consult your doctor.

 

There is insufficient information on the use of Trilavir D Tablet while breastfeeding. Please consult your doctor before use.

 

It is uncertain whether Trilavir D Tablet affects your ability to drive. Avoid driving if you experience drowsiness, dizziness, or reduced alertness.

 

Limited data is available on the safety of Trilavir D Tablet in patients with kidney disease. Dose adjustments may be necessary. Please consult your doctor.

 

Trilavir D Tablet should be used with caution in patients with liver disease. Dose adjustments may be required based on the severity of the condition. Please consult your doctor.

 

 

FAQs:

Q: Can I take Trilavir D Tablet on an empty stomach?
A: Yes, but taking it with food may help reduce nausea.

 

Q: How long does it take for Trilavir D Tablet to work?
A: Viral suppression typically begins within a few weeks, but full benefits require consistent use.

 

Q: Can I consume alcohol while taking Trilavir D Tablet?
A: No, alcohol can increase the risk of liver toxicity and interact with the medication.

 

Q: Is Trilavir D Tablet safe during pregnancy?
A: Yes, but only under medical supervision as part of an HIV prevention protocol.

 

Q: What happens if I stop taking Trilavir D Tablet?
A: Stopping medication abruptly can lead to drug resistance and worsening of HIV infection.

 

 

Related Lab Tests:

• CD4 Count Test: Measures immune function and disease progression.
• HIV Viral Load Test: Determines the level of HIV in the bloodstream.
• Liver Function Test (LFT): Monitors liver health during treatment.
• Complete Blood Count (CBC): Checks for anemia and blood disorders.
• Kidney Function Test (KFT): Ensures the kidneys are functioning properly.

Additional information

Manufacturer	Laurus Labs