Description
Generic Name:
Spegra – 90 Tablet contains a combination of Dolutegravir, Emtricitabine, and Tenofovir Alafenamide.
Composition:
Each Spegra – 90 Tablet consists of:
- Dolutegravir (50 mg)
- Emtricitabine (200 mg)
- Tenofovir Alafenamide (25 mg)
Indication:
Spegra – 90 Tablet is indicated for the treatment of HIV-1 infection in adults and adolescents aged 12 years and older weighing at least 40 kg. It helps to control the infection, reduce the viral load, and improve immune system function.
Storage Instructions:
- Store at room temperature (15°C – 30°C) in a dry place.
- Keep away from direct sunlight and moisture.
- Store in the original container with the lid tightly closed.
- Keep out of reach of children.
Uses of Spegra – 90 Tablet:
- Manages HIV-1 infection effectively.
- Reduces the amount of HIV in the blood, preventing complications.
- Boosts the immune system to fight infections.
- Lowers the risk of HIV-related illnesses.
Benefits of Spegra – 90 Tablet:
- Effective viral suppression: Reduces the viral load, preventing the progression of HIV.
- Convenient once-daily dosage: Simplifies treatment adherence.
- Fewer side effects: Compared to older HIV medications, it has improved tolerability.
- Supports immune health: Helps maintain a stronger immune response.
Side Effects:
Common side effects may include:
- Headache
- Nausea
- Diarrhea
- Fatigue
- Insomnia
Serious Side Effects Include:
- Liver problems (yellowing of skin/eyes, dark urine)
- Lactic acidosis (muscle pain, rapid breathing, drowsiness)
- Kidney problems (changes in urine output, swelling in feet/ankles)
- Depression or mood changes
- Severe allergic reactions (rash, swelling of the face, difficulty breathing)
How to Use Spegra – 90 Tablet:
- Take one tablet daily with or without food, as prescribed by your doctor.
- Swallow the tablet whole with water.
- Do not miss doses to ensure effective viral suppression.
How Spegra – 90 Tablet Works:
Spegra – 90 Tablet contains three antiretroviral drugs that work by preventing HIV from multiplying in the body:
- Dolutegravir: Blocks the HIV integrase enzyme, preventing virus replication.
- Emtricitabine & Tenofovir Alafenamide: Inhibit the reverse transcriptase enzyme, stopping the virus from multiplying.
What If You Forget to Take the Medicine?
- Take the missed dose as soon as you remember.
- If it is almost time for your next dose, skip the missed dose.
- Do not take a double dose to make up for a missed one.
Quick Tips:
- Always take the medicine as prescribed by your doctor.
- Do not stop taking it without consulting your doctor.
- Regular blood tests are necessary to monitor HIV progression.
- Maintain a healthy lifestyle, including a balanced diet and regular exercise.
- Use safe practices to prevent spreading HIV to others.

Alcohol
Caution is advised when consuming alcohol with Spegra-90 Tablet. Please consult your doctor for guidance.
Pregnancy
Spegra-90 Tablet is unsafe to use during pregnancy due to potential harm to the developing baby. It may only be prescribed in life-threatening situations where benefits outweigh the risks. Please consult your doctor.

Breastfeeding
There is insufficient information on the use of Spegra-90 Tablet while breastfeeding. Please consult your doctor before use.

Driving
It is uncertain whether Spegra-90 Tablet affects your ability to drive. Avoid driving if you experience drowsiness, dizziness, or reduced alertness.

Kidney
Limited data is available on the safety of Spegra-90 Tablet in patients with kidney disease. Dose adjustments may be necessary. Please consult your doctor.

Liver
Spegra-90 Tablet should be used with caution in patients with liver disease. Dose adjustments may be required based on the severity of the condition. Please consult your doctor.
FAQs:
Q: Can I stop taking Spegra – 90 Tablet if I feel better?
A: No, stopping the medicine can cause HIV to multiply and develop resistance. Always follow your doctor’s advice.
Q: Can Spegra – 90 Tablet cure HIV/AIDS?
A: No, it does not cure HIV/AIDS but helps in controlling the virus and improving the quality of life.
Q: Is it safe during pregnancy and breastfeeding?
A: Consult your doctor, as the benefits and risks must be evaluated based on individual cases.
Q: Can I drink alcohol while taking Spegra – 90 Tablet?
A: It is best to limit or avoid alcohol as it may increase the risk of liver problems and side effects.
Q: Does Spegra – 90 Tablet have any drug interactions?
A: Yes, certain medications may interact with Spegra, including rifampin, anticonvulsants, and herbal supplements. Inform your doctor about any other medicines you are taking.
Related Lab Tests:
- HIV viral load test
- CD4 count test
- Liver function test
- Kidney function test
- Blood glucose and lipid profile
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