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Velasof is a medication that combines two active ingredients, sofosbuvir and velpatasvir. It is primarily used for the treatment of chronic hepatitis C virus (HCV) infection.

Requires Prescription



Here information about the use, directions, benefits, mechanism of action, and safety advice related to Velasof:


  • Velasof is prescribed for individuals with chronic HCV infection.
  • It is effective against various genotypes of the hepatitis C virus.
  • Velasof may be recommended for treatment-naive patients or those who have not responded to previous HCV treatment.

Directions of Use:

  • Velasof is typically taken orally as a tablet.
  • The recommended dosage is one tablet taken once a day.
  • It can be taken with or without food, as advised by your healthcare professional.
  • The duration of treatment may vary depending on factors such as HCV genotype, liver condition, and prior treatment history.


  • Velasof provides a combination therapy in a single tablet, simplifying the treatment regimen for chronic hepatitis C.
  • It offers high cure rates, often exceeding 95%, across different genotypes of HCV infection.
  • Successful treatment with Velasof can lead to sustained virologic response (SVR), indicating the absence of detectable HCV RNA in the blood, which signifies a cure for HCV infection.
  • Achieving SVR can prevent liver damage, reduce the risk of cirrhosis, hepatocellular carcinoma, and improve overall liver health.

Mechanism of Action:

  • Sofosbuvir is a nucleotide analogue inhibitor of the HCV NS5B polymerase. It acts by blocking the replication of the hepatitis C virus.
  • Velpatasvir is an NS5A inhibitor that targets a different viral protein essential for HCV replication. It inhibits the assembly and release of new virus particles.

Safety Advice:

  • Velasof should only be taken under the supervision and prescription of a healthcare professional experienced in the treatment of HCV.
  • Inform your healthcare provider about any other medications, supplements, or herbal products you are taking, as they may interact with Velasof.
  • Attend regular follow-up appointments and medical check-ups to monitor your response to treatment and liver function.
  • Adhere to the prescribed dosage and duration of Velasof treatment to maximize its effectiveness.

Additional information


Hetero Healthcare Limited


28 Tab


Sofosbuvir 400 Mg and Velpatasvir 100 Mg

What is the valid prescription?