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Twinaqt Dolutegravir + Lamivudine 50mg + 300mg is a combination medication used for the treatment of HIV infection.

Requires Prescription



Here’s information about the use, directions, benefits, and safety advice related to Trustiva::


  • This medication is prescribed for the management of HIV-1 infection in adults and adolescents. It helps to reduce the viral load, increase CD4 cell counts, and improve immune function.

Directions of Use:

  • The dosage and administration instructions should be determined by your healthcare provider and may vary based on individual factors. Typically, the medication is taken orally as one tablet once daily, with or without food. It is important to follow the instructions provided by your doctor or the medication label.


  • The combination of Dolutegravir and Lamivudine is highly effective in suppressing the replication of the HIV virus. It helps to reduce the viral load in the body, restore and preserve immune function, and prevent the progression of HIV-related complications. By consistently taking the medication as prescribed, individuals with HIV can achieve and maintain viral suppression, leading to improved health outcomes and a reduced risk of transmitting the virus to others.

How it works:

  • Dolutegravir belongs to a class of medications called integrase strand transfer inhibitors (INSTIs). It works by blocking the integrase enzyme, which is responsible for incorporating the viral DNA into the DNA of the infected cells. By inhibiting this enzyme, Dolutegravir prevents the integration of the viral DNA into the host cell DNA, thus inhibiting viral replication. Lamivudine belongs to the
    class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of the HIV virus. By blocking this enzyme, Lamivudine prevents the conversion of viral RNA into DNA, further hindering viral replication.

Safety Advice:

  • It is important to take this medication consistently and as prescribed by your healthcare provider. Adherence to the treatment regimen is crucial for its effectiveness. Inform your healthcare provider about any other medications you are taking, including over-the-counter drugs and supplements, as there may be potential drug interactions. Common side effects of this combination medication may include headache, nausea, diarrhea, fatigue, and insomnia. However, not everyone experiences these side effects. Regular monitoring of liver function, kidney function, and HIV viral load is typically recommended during treatment

Please note that the information provided here is a general overview, and it is important to consult with your healthcare provider for personalized guidance and specific instructions related to your HIV treatment. They will be able to provide you with the most accurate and up-to-date information based on your individual needs and medical history.

Additional information


Emcure Pharmaceuticals Limited


30 Tab


Dolutegravir+lamivudine 50mg+300 Mg

What is the valid prescription?