Description
Generic Name:
Dolutegravir
Composition:
Each Intelavir Tablet contains:
- Dolutegravir (50mg): An integrase strand transfer inhibitor (INSTI) that blocks HIV replication by preventing the virus from integrating into human DNA.
- Excipients: [List of inactive ingredients such as binders, stabilizers, and coatings].
Indication:
Intelavir Tablet is indicated for:
- HIV-1 Infection Treatment: Used as part of combination antiretroviral therapy (ART) for managing HIV-1 in adults and adolescents.
- Post-Exposure Prophylaxis (PeP): Sometimes prescribed for individuals exposed to HIV through occupational or non-occupational means.
Storage Instructions:
- Store at room temperature (15-30°C) in a dry place.
- Keep away from direct sunlight, moisture, and heat.
- Store in original packaging to protect from light.
- Keep out of reach of children and pets.
Uses of the Medicine:
- HIV Management: Helps reduce viral load and increase CD4 cell count in HIV-positive individuals.
- Combination Therapy: Used with other antiretroviral drugs for effective treatment.
- Post-Exposure Prevention: Can be part of a PeP regimen to lower the risk of HIV infection after exposure.
Benefits of the Medicine:
- Highly Effective: Rapidly reduces HIV viral load.
- Once-Daily Dosing: Enhances treatment adherence.
- Fewer Drug Interactions: Compared to other antiretroviral medications.
- Well-Tolerated: Lower risk of severe side effects.
Side Effects:
Common side effects may include:
- Nausea, vomiting, or diarrhea
- Headache or dizziness
- Fatigue or weakness
- Insomnia or abnormal dreams
- Mild rash or skin irritation
Serious Side Effects Include:
Seek immediate medical attention if you experience:
- Severe allergic reactions (swelling of the face, lips, or throat, difficulty breathing).
- Liver toxicity (yellowing of skin/eyes, dark urine, abdominal pain).
- Mental health effects (severe depression, suicidal thoughts).
- Lactic acidosis (unexplained muscle pain, rapid breathing, drowsiness).
How to Use the Medicine:
- Take one tablet once daily, as prescribed by your doctor.
- Swallow whole with water; do not crush or chew.
- Can be taken with or without food.
- If used for PeP, must be taken consistently for 28 days.
- Adherence is crucial for effectiveness; do not miss doses.
How the Medicine Works:
Intelavir Tablet works by inhibiting the HIV integrase enzyme, preventing the virus from incorporating its genetic material into human cells. This stops viral replication and reduces the viral load in the bloodstream.
What If You Forget to Take the Medicine?
- Take the missed dose as soon as possible.
- If it is close to the next scheduled dose, skip the missed dose.
- Do not take a double dose to compensate for a missed one.
Quick Tips:
- Take Intelavir Tablet at the same time each day.
- Avoid alcohol and recreational drugs, which may worsen side effects.
- Use condoms and other protective measures to prevent HIV transmission.
- Regular follow-up tests are necessary to monitor effectiveness.
Safety Advice
Alcohol
Caution is advised when consuming alcohol with Intelavir Tablet. Please consult your doctor for guidance.
Pregnancy
Intelavir Tablet is unsafe to use during pregnancy due to potential harm to the developing baby. It may only be prescribed in life-threatening situations where benefits outweigh the risks. Please consult your doctor.
Breastfeeding
There is insufficient information on the use of Intelavir Tablet while breastfeeding. Please consult your doctor before use.
Driving
It is uncertain whether Intelavir Tablet affects your ability to drive. Avoid driving if you experience drowsiness, dizziness, or reduced alertness.
Kidney
Limited data is available on the safety of Intelavir Tablet in patients with kidney disease. Dose adjustments may be necessary. Please consult your doctor.
Liver
Intelavir Tablet should be used with caution in patients with liver disease. Dose adjustments may be required based on the severity of the condition. Please consult your doctor.
FAQs:
Q: Can Intelavir Tablet cure HIV?
A: No, it helps control the virus but does not cure HIV. Lifelong treatment is required.
Q: Can pregnant or breastfeeding women take Intelavir Tablet?
A: Consult a doctor before use; it may be safe, but medical guidance is essential.
Q: How long does it take for Intelavir Tablet to work?
A: A reduction in viral load can be observed within a few weeks of consistent use.
Q: Can Intelavir Tablet be taken alone for HIV treatment?
A: No, it must be used in combination with other antiretroviral drugs.
Related Lab Tests:
- HIV Viral Load Test (to monitor treatment effectiveness).
- CD4 Cell Count (to assess immune function).
- Liver and Kidney Function Tests (to monitor potential toxicity).
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