Description
Generic Name:
Instgra contains Dolutegravir as its active ingredient.
Composition:
Each tablet of Instgra contains:
- Dolutegravir (50 mg)
- Excipients: (as per manufacturer’s formulation)
Indication:
Instgra is indicated for:
- HIV-1 Infection: Used in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and adolescents.
- Helps maintain viral suppression and improves immune function.
Storage Instructions:
- Store at room temperature (15-30°C).
- Keep in a dry place, away from moisture and direct sunlight.
- Keep out of reach of children.
Uses of the Medicine:
- Helps control HIV infection and prevents disease progression.
- Reduces viral load and prevents the virus from multiplying.
- Helps improve immune function and CD4 cell count.
Benefits of the Medicine:
- Potent integrase inhibitor for HIV treatment.
- Reduces the risk of HIV transmission.
- Has a high genetic barrier to resistance.
- Well tolerated with a low risk of side effects.
Side Effects:
Common side effects include:
- Nausea
- Diarrhea
- Headache
- Dizziness
- Fatigue
Serious Side Effects Include:
- Liver toxicity (hepatitis, jaundice)
- Hypersensitivity reactions (rash, fever, organ dysfunction)
- Depression or mood changes
- Increased liver enzymes
- Sleep disturbances (insomnia)
How to Use the Medicine:
- Take one tablet once daily, with or without food.
- If taken with certain other medications, a twice-daily dose may be required (as per doctor’s instructions).
- Swallow the tablet whole with water.
- Follow the doctor’s prescribed dosage strictly.
How the Medicine Works:
Instgra contains Dolutegravir, an integrase strand transfer inhibitor (INSTI), which works by:
- Blocking the HIV integrase enzyme, preventing the virus from inserting its genetic material into human DNA.
- Suppressing HIV viral replication, reducing viral load.
- Enhancing immune function by maintaining CD4 cell count.
What If You Forget to Take the Medicine?
- Take the missed dose as soon as you remember.
- If it’s close to the next dose, skip the missed dose.
- Do not take a double dose to make up for the missed one.
Quick Tips:
- Take Instgra at the same time every day for best results.
- Do not stop taking the medicine without consulting your doctor.
- Avoid iron or calcium supplements within 6 hours before or 2 hours after taking Instgra.
- Regularly monitor liver function during treatment.
- Inform your doctor if you experience severe mood changes or depression.
Safety Advice
Alcohol
Caution is advised when consuming alcohol with Instgra Tablet. Please consult your doctor for guidance.
Pregnancy
Instgra Tablet is unsafe to use during pregnancy due to potential harm to the developing baby. It may only be prescribed in life-threatening situations where benefits outweigh the risks. Please consult your doctor.
Breastfeeding
There is insufficient information on the use of Instgra Tablet while breastfeeding. Please consult your doctor before use.
Driving
It is uncertain whether Instgra Tablet affects your ability to drive. Avoid driving if you experience drowsiness, dizziness, or reduced alertness.
Kidney
Limited data is available on the safety of Instgra Tablet in patients with kidney disease. Dose adjustments may be necessary. Please consult your doctor.
Liver
Instgra Tablet should be used with caution in patients with liver disease. Dose adjustments may be required based on the severity of the condition. Please consult your doctor.
FAQs:
Q: Can Instgra cure HIV?
A: No, but it effectively controls HIV infection and prevents its progression.
Q: Can I drink alcohol while taking Instgra?
A: Limit alcohol intake to reduce the risk of liver damage.
Q: Can pregnant women take Instgra?
A: Consult your doctor before use; it may be prescribed in pregnancy if the benefits outweigh the risks.
Q: How long does it take for Instgra to work?
A: It starts working within a few weeks, but a significant reduction in viral load occurs within 3-6 months.
Related Lab Tests:
- HIV-1 RNA Test
- Kidney Function Test (Creatinine, eGFR)
- Liver Function Test (LFTs)
- CD4 Count
Other Resources
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