Description
Generic Name:
Spegra PEP Tablet contains a combination of potent antiretroviral medications used for Post-Exposure Prophylaxis (PEP) to reduce the risk of HIV infection.
Composition:
Each Spegra PEP Tablet contains:
- Dolutegravir – an integrase inhibitor that prevents HIV from replicating.
- Tenofovir Disoproxil Fumarate – a nucleotide reverse transcriptase inhibitor (NRTI) that blocks HIV replication.
- Lamivudine – another NRTI that stops the virus from multiplying in the body.
Indication:
Spegra PEP Tablet is indicated for HIV Post-Exposure Prophylaxis (PEP) to prevent HIV infection after potential exposure through unprotected sex, needlestick injuries, or other high-risk situations.
Storage Instructions:
- Store at room temperature (15-25°C).
- Keep away from direct sunlight and moisture.
- Keep out of reach of children and pets.
- Do not use expired tablets.
Uses of the Medicine:
- PEP treatment: Helps prevent HIV infection if started within 72 hours of exposure.
- Reduces viral replication: Lowers the risk of the virus establishing an infection.
- Supports immune defense: Helps maintain immune function after potential HIV exposure.
Benefits of the Medicine:
- High effectiveness when taken within 72 hours of exposure.
- Once-daily dosing for ease of use.
- Well-tolerated with minimal side effects in most users.
- Proven protection when the full 28-day course is completed.
Side Effects:
Common side effects include:
- Nausea
- Headache
- Fatigue
- Diarrhea
- Insomnia
Serious Side Effects Include:
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Liver problems (yellowing of skin/eyes, dark urine)
- Lactic acidosis (weakness, irregular heartbeat, muscle pain)
- Kidney dysfunction (decreased urination, swelling in legs/ankles)
How to Use the Medicine:
- Take one tablet daily with or without food.
- Swallow the tablet whole with a glass of water.
- Complete the full 28-day treatment course.
- Do not stop the medication without consulting a doctor.
How the Medicine Works:
Spegra PEP Tablet contains three antiretroviral drugs that work together to block HIV replication, preventing the virus from integrating into human cells and establishing an infection.
What If You Forget to Take the Medicine?
- Take the missed dose as soon as you remember.
- If it is close to your next dose, skip the missed dose and continue as scheduled.
- Do not take a double dose to make up for the missed one.
Quick Tips:
- Start PEP within 72 hours of exposure for maximum effectiveness.
- Complete the 28-day course to ensure full protection.
- Use condoms and safe practices to prevent further exposure.
- Stay in touch with your doctor for regular follow-ups.
Safety Advice
Alcohol
⚠️ CAUTION
Caution is advised when consuming alcohol with Spegra Tablet. Please consult your doctor for guidance.
Pregnancy
❗ CONSULT YOUR DOCTOR
Spegra Tablet is unsafe to use during pregnancy due to potential harm to the developing baby. It may only be prescribed in life-threatening situations where benefits outweigh the risks. Please consult your doctor.
Breastfeeding
❗ CONSULT YOUR DOCTOR
There is insufficient information on the use of Spegra Tablet while breastfeeding. Please consult your doctor before use.
Driving
❗ CONSULT YOUR DOCTOR
It is uncertain whether Spegra Tablet affects your ability to drive. Avoid driving if you experience drowsiness, dizziness, or reduced alertness.
Kidney
❗ CONSULT YOUR DOCTOR
Limited data is available on the safety of Spegra Tablet in patients with kidney disease. Dose adjustments may be necessary. Please consult your doctor.
Liver
⚠️ CAUTION
Spegra Tablet should be used with caution in patients with liver disease. Dose adjustments may be required based on the severity of the condition. Please consult your doctor.
FAQs:
Q: How soon should I take Spegra PEP after exposure?
A: Ideally, within 72 hours of potential HIV exposure, the sooner, the better.
Q: Can I stop taking PEP if I feel fine?
A: No, you must complete the full 28-day course for maximum protection.
Q: Does Spegra PEP guarantee 100% protection against HIV?
A: While highly effective, PEP is not 100% foolproof. Safe sex and prevention methods should still be followed.
Related Lab Tests:
- HIV Testing (Baseline, 4 Weeks, 12 Weeks Post-Exposure)
- Liver and Kidney Function Tests
- Complete Blood Count (CBC)
- Hepatitis B and C Screening
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