Description
Generic Name: Dolutegravir, Emtricitabine, and Tenofovir Alafenamide
Composition: Each Alafevir DE Pep Tablet contains:
- Dolutegravir (50 mg)
- Emtricitabine (200 mg)
- Tenofovir Alafenamide (25 mg)
- Excipients
Indication:
Alafevir DE Pep Tablet is indicated for post-exposure prophylaxis (PEP) to reduce the risk of Human Immunodeficiency Virus (HIV) infection in individuals exposed to HIV through sexual contact, occupational exposure, or other means. It is used as part of a comprehensive HIV prevention strategy.
Storage Instructions:
- Store at room temperature (15°C to 30°C).
- Keep in a cool, dry place, away from direct sunlight and moisture.
- Store in the original container and keep the lid tightly closed.
- Keep out of reach of children.
Uses of Alafevir DE Pep Tablet:
- Prevents HIV infection following potential exposure.
- Reduces the risk of HIV transmission.
- Supports post-exposure prophylaxis when taken within 72 hours of exposure.
Benefits of Alafevir DE Pep Tablet:
- Highly effective in preventing HIV infection after exposure.
- Convenient once-daily dosing regimen.
- Combines three antiretroviral agents for comprehensive protection.
Side Effects: Common side effects include:
- Nausea
- Headache
- Fatigue
- Diarrhea
- Dizziness
Serious Side Effects Include:
- Severe allergic reactions (rash, fever, difficulty breathing)
- Lactic acidosis (unusual muscle pain, rapid breathing, nausea)
- Liver toxicity (jaundice, dark urine)
- Kidney problems (decreased urine output, swelling)
- Depression or mood changes
Seek immediate medical attention if you experience any serious side effects.
How to Use Alafevir DE Pep Tablet:
- Take as prescribed by your healthcare provider.
- Swallow the tablet whole with a glass of water.
- Can be taken with or without food.
- Start within 72 hours of HIV exposure and continue for 28 days.
- Take at the same time each day for maximum effectiveness.
How Alafevir DE Pep Tablet Works: Alafevir DE Pep Tablet combines three antiretroviral agents:
- Dolutegravir: An integrase strand transfer inhibitor (INSTI) that blocks the integration of viral DNA into the host genome.
- Emtricitabine: A nucleoside reverse transcriptase inhibitor (NRTI) that prevents viral replication.
- Tenofovir Alafenamide: A prodrug of tenofovir that disrupts viral DNA synthesis and reduces the viral load.
Together, these components prevent the HIV virus from multiplying and establishing an infection.
What If You Forget to Take Alafevir DE Pep Tablet?
- Take the missed dose as soon as you remember.
- If it is close to your next dose, skip the missed dose and resume your regular schedule.
- Do not double the dose to make up for a missed one.
- Consistent adherence is crucial for effectiveness.
Quick Tips:
- Start Alafevir DE Pep Tablet within 72 hours of potential HIV exposure.
- Complete the full 28-day course, even if you feel well.
- Inform your doctor of any other medications or health conditions.
- Avoid alcohol consumption to reduce the risk of side effects.
- Regular follow-up and HIV testing are essential during and after PEP.
Safety Advice
Alcohol
Caution is advised when consuming alcohol with Alafevir DE Tablet. Please consult your doctor for guidance.
Pregnancy
Alafevir DE Tablet is unsafe to use during pregnancy due to potential harm to the developing baby. It may only be prescribed in life-threatening situations where benefits outweigh the risks. Please consult your doctor.
Breastfeeding
There is insufficient information on the use of Alafevir DE Tablet while breastfeeding. Please consult your doctor before use.
Driving
It is uncertain whether Alafevir DE Tablet affects your ability to drive. Avoid driving if you experience drowsiness, dizziness, or reduced alertness.
Kidney
Limited data is available on the safety of Alafevir DE Tablet in patients with kidney disease. Dose adjustments may be necessary. Please consult your doctor.
Liver
Alafevir DE Tablet should be used with caution in patients with liver disease. Dose adjustments may be required based on the severity of the condition. Please consult your doctor.
FAQs:
Q: How effective is Alafevir DE Pep Tablet for HIV prevention?
A: It is highly effective when taken correctly within 72 hours of exposure and completed for 28 days.
Q: Can I stop taking the medicine if I feel better?
A: No, you must complete the entire course to maximize protection against HIV infection.
Q: Is Alafevir DE Pep Tablet safe during pregnancy?
A: Inform your doctor if you are pregnant or planning to conceive. They will weigh the benefits and risks.
Q: Can I take Alafevir DE Pep Tablet with other medications?
A: Always inform your healthcare provider about all medications and supplements to avoid drug interactions.
Related Lab Tests:
- HIV testing (before, during, and after PEP)
- Liver function tests
- Kidney function tests
- Complete blood count (CBC)
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