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Trilavir D Tablet (ART) Bottle Front View

Trilavir D Tablet (ART) Bottle Back View

Trilavir D ART Tablet

Q: How does Trilavir D Tablet work to treat HIV?

Trilavir D works by blocking the reverse transcriptase enzyme HIV-1 needs to replicate. Lamivudine and Zidovudine (NRTIs) act as faulty building blocks that terminate HIV DNA replication. Nevirapine (NNRTI) binds directly to the enzyme and disrupts its structure, blocking a critical step in the HIV replication cycle.

Q: What is the recommended dosage of Trilavir D Tablet?

The usual dose is one Trilavir D Tablet twice daily, morning and evening, or exactly as prescribed by your doctor. It can be taken with or without food. Always take at the same times each day and never skip doses, as this can lead to drug resistance.

Q: Can Trilavir D Tablet cure HIV or AIDS?

No. Trilavir D Tablet does not cure HIV or AIDS. It helps control HIV-1 viral load and supports CD4 cell recovery but must be taken continuously as prescribed. Stopping treatment without medical advice can lead to viral rebound and drug resistance.

Q: Does Trilavir D Tablet interact with other medicines?

Yes. Rifampicin significantly reduces Nevirapine levels. Antacids, iron supplements, alcohol, other antiretrovirals, anti-epileptics, azole antifungals, and oral contraceptives may also interact. Always inform your doctor about all medicines before starting Trilavir D.

Q: Is Trilavir D Tablet safe during pregnancy or breastfeeding?

Use during pregnancy requires careful medical evaluation. Nevirapine has been used in preventing mother-to-child HIV transmission under supervision. Breastfeeding is not recommended without medical advice. Always consult your doctor if pregnant, planning to conceive, or breastfeeding.

Q: What tests are needed before and during Trilavir D Tablet treatment?

Before starting: HIV viral load test, CD4 count, liver function tests (LFT), complete blood count (CBC), and kidney function tests (KFT). During treatment, these are repeated at 4u20138 weeks initially, then every 3u20136 months to monitor viral suppression and drug safety.

Q: Who should not take Trilavir D Tablet?

People allergic to Lamivudine, Zidovudine, or Nevirapine should not take Trilavir D. It should be avoided in moderate-to-severe liver disease, severe kidney impairment, or history of serious skin reactions to NNRTIs. Do not take with Rifampicin without medical guidance.

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Original price was: ₹4,199.Current price is: ₹1,600.

You Save ₹2,599 (62%)

Active Composition (per tablet)

Lamivudine (150mg)

Zidovudine (300mg)

Nevirapine (200mg)

Trilavir D Tablet (Lamivudine 150mg + Zidovudine 300mg + Nevirapine 200mg) is a prescription HIV medicine used as part of doctor-prescribed antiretroviral therapy (ART) for the treatment of HIV-1 infection. It is a fixed-dose combination (FDC) tablet containing two nucleoside reverse transcriptase inhibitors (NRTIs) and one non-nucleoside reverse transcriptase inhibitor (NNRTI) that work together to suppress HIV-1 viral load and support long-term HIV management under medical supervision.

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Uses & Benefits

Used in the treatment of HIV-1 infection in adults as part of a doctor-prescribed antiretroviral therapy (ART) regimen.
Helps reduce the amount of HIV-1 virus in the bloodstream and keeps viral load under control.
Supports improvement in CD4 cell count, strengthening the immune system over time.
Prevents HIV infection from advancing to AIDS with consistent long-term use.
Reduces the risk of developing HIV-related opportunistic infections and complications.

Key Benefits

Combines Lamivudine, Zidovudine, and Nevirapine in a single fixed-dose tablet, reducing pill burden.
Targets the HIV reverse transcriptase enzyme at two different sites for stronger viral suppression.
Supports consistent long-term HIV management when taken as prescribed every day.
Based on a WHO and NACO-recommended antiretroviral regimen used in India's National AIDS Control Programme.
Offers a significantly more affordable option compared to branded ART medicines for long-term treatment.

How it works?

NRTI Action — Lamivudine & Zidovudine

Act as faulty building blocks that HIV incorporates into its DNA chain, terminating replication and stopping the virus from multiplying inside the body.

NNRTI Action — Nevirapine

Binds directly to the reverse transcriptase enzyme, locking its structure and blocking HIV from converting viral RNA into DNA.

Combined Viral Suppression

Targeting reverse transcriptase at two sites simultaneously makes it harder for HIV to replicate or develop resistance, resulting in sustained viral load suppression and CD4 recovery.

How to take?

Take one Trilavir D Tablet twice daily, morning and evening, or exactly as prescribed by your doctor.

Can be taken with or without food; taking with a light meal helps reduce nausea in early weeks.

Swallow the tablet whole with a full glass of water. Do not crush, break, or chew.

Take at the same time every day to maintain steady drug levels and prevent resistance.

Do not skip doses or stop treatment without consulting your doctor, even if you feel well.

Safety Advice

🍺

Alcohol

Caution

Caution is advised when consuming alcohol with Trilavir D Tablet. Please consult your doctor for guidance.

🤰

Pregnancy

Consult Your Doctor

Trilavir D Tablet is unsafe to use during pregnancy due to potential harm to the developing baby. It may only be prescribed in life-threatening situations where benefits outweigh the risks. Please consult your doctor.

🤱

Breastfeeding

Consult Your Doctor

There is insufficient information on the use of Trilavir D Tablet while breastfeeding. Please consult your doctor before use.

🚗

Driving

Consult Your Doctor

It is uncertain whether Trilavir D Tablet affects your ability to drive. Avoid driving if you experience drowsiness, dizziness, or reduced alertness.

🫘

Kidney

Consult Your Doctor

Limited data is available on the safety of Trilavir D Tablet in patients with kidney disease. Dose adjustments may be necessary. Please consult your doctor.

🫀

Liver

Consult Your Doctor

Trilavir D Tablet should be used with caution in patients with liver disease. Dose adjustments may be required based on the severity of the condition. Please consult your doctor.

Side Effects

⚡ Common Side Effects

Common side effects includes:

Gastrointestinal Issues: Nausea, vomiting, diarrhea, or bloating.

Neurological Effects: Dizziness, headache, or fatigue.

Skin Reactions: Rash, itching, or mild hypersensitivity.

Muscle and Joint Pain: Common during the first few weeks of treatment.

⚠️ Serious – Seek Help Immediately

Serious side effects include:

Severe Allergic Reactions: Swelling of the face, lips, or throat; difficulty breathing.

Lactic Acidosis: Unusual weakness, muscle pain, rapid breathing, nausea, or irregular heartbeat.

Liver Toxicity: Yellowing of skin/eyes, dark urine, severe stomach pain.

Bone Marrow Suppression: Low blood cell counts, leading to infections or anemia.

Stevens-Johnson Syndrome (SJS): Severe skin reactions, blistering, or peeling.

Frequently Asked Questions

What is Trilavir D Tablet used for?

›

Trilavir D Tablet is used to treat HIV-1 infection in adults as part of combination antiretroviral therapy (ART). It contains three antiretroviral medicines — Lamivudine 150mg, Zidovudine 300mg, and Nevirapine 200mg — that work together to suppress HIV-1 viral load, improve CD4 cell count, and prevent the disease from progressing to AIDS. It is taken under medical supervision as part of a doctor-prescribed HIV treatment plan.

What is the composition of Trilavir D Tablet?

›

Each Trilavir D Tablet contains Lamivudine 150mg, Zidovudine 300mg, and Nevirapine 200mg. Lamivudine and Zidovudine belong to the NRTI (nucleoside reverse transcriptase inhibitor) class, while Nevirapine is an NNRTI (non-nucleoside reverse transcriptase inhibitor). Together they form a fixed-dose combination (FDC) that targets the HIV reverse transcriptase enzyme at two different binding sites, making it harder for the virus to develop resistance when taken consistently as prescribed.

How does Trilavir D Tablet work to treat HIV?

›

Trilavir D Tablet works by blocking the reverse transcriptase enzyme that HIV-1 needs to copy its genetic material and multiply inside the body. Lamivudine and Zidovudine (NRTIs) act as faulty building blocks that the virus mistakenly incorporates into its DNA chain, stopping replication. Nevirapine (NNRTI) binds directly to the reverse transcriptase enzyme and disrupts its structure. This dual mechanism reduces HIV viral load in the bloodstream and allows the immune system’s CD4 cells to recover.

What is the recommended dosage of Trilavir D Tablet?

›

The usual dose of Trilavir D Tablet is one tablet taken twice daily, or exactly as prescribed by your doctor. The tablet can be taken with or without food, though taking it with a light meal may help reduce nausea when starting treatment. Always take Trilavir D at the same times each day to maintain steady drug levels and support ART adherence. Never skip doses, as this can lead to drug resistance.

Can Trilavir D Tablet cure HIV or AIDS?

›

No. Trilavir D Tablet does not cure HIV infection or AIDS. It helps control HIV-1 viral load, supports CD4 cell recovery, and prevents the disease from advancing to AIDS — but must be taken continuously and consistently as prescribed by your doctor. Stopping treatment without medical advice can lead to rapid viral rebound, drug resistance, and worsening of HIV infection.

What are the common and serious side effects of Trilavir D Tablet?

›

Common side effects include nausea, vomiting, headache, fatigue, dizziness, diarrhoea, and skin rash, especially during the first few weeks. Serious side effects requiring immediate medical attention include severe skin reactions (Stevens-Johnson Syndrome), lactic acidosis (unusual muscle pain, weakness, rapid breathing), liver toxicity (yellowing of skin or eyes, dark urine, abdominal pain), bone marrow suppression, and severe allergic reactions. Contact your doctor immediately if any serious symptoms appear.

Does Trilavir D Tablet interact with other medicines?

›

Yes. Trilavir D Tablet can interact with several medicines. Rifampicin (used for tuberculosis) significantly reduces Nevirapine blood levels, making the combination less effective. Antacids and iron supplements may affect absorption. Alcohol increases the risk of liver toxicity. Other antiretrovirals, anti-epileptics, azole antifungals, and oral contraceptives may also interact. Always inform your doctor about all prescription medicines, over-the-counter drugs, herbal supplements, and vitamins you are taking before starting Trilavir D.

Is Trilavir D Tablet safe during pregnancy or breastfeeding?

›

Trilavir D Tablet use during pregnancy requires careful medical evaluation. Nevirapine has been used in preventing mother-to-child transmission (PMTCT) of HIV under medical supervision, but the safety of the full combination must be assessed by your doctor based on gestational age and maternal health. Breastfeeding while taking Trilavir D is not recommended without medical advice, as antiretroviral medicines can pass into breast milk. Always consult your doctor before use if you are pregnant, planning to conceive, or breastfeeding.

What tests are needed before and during Trilavir D Tablet treatment?

›

Before starting Trilavir D, your doctor will typically recommend an HIV viral load test, a CD4 count test, liver function tests (LFT), complete blood count (CBC), and kidney function tests (KFT). During treatment, these tests are repeated at regular intervals — usually at 4–8 weeks initially, then every 3–6 months — to monitor viral suppression, immune recovery, and safety of all three drug components. Regular monitoring is essential for effective long-term ART management.

Who should not take Trilavir D Tablet?

›

Trilavir D Tablet should not be taken by people who are allergic to Lamivudine, Zidovudine, Nevirapine, or any ingredient in the tablet. It should be used with caution — or avoided — in patients with moderate-to-severe liver disease, severe kidney impairment, or a history of serious skin reactions to Nevirapine or any NNRTI. It should not be taken alongside certain tuberculosis medicines like Rifampicin without a doctor’s guidance. Always disclose your full medical history and all medicines to your doctor before starting treatment.

Manufacturer

Trilavir D Tablet is manufactured by Laurus Labs Limited, one of India’s leading pharmaceutical companies, headquartered in Hyderabad, Telangana. Founded in 2005, Laurus Labs is internationally recognised as a major producer of active pharmaceutical ingredients (APIs) and finished formulations for antiretroviral (ARV) medicines, supplying HIV treatments to public-health programmes across India, sub-Saharan Africa, and other regions under agreements with global health bodies including the Clinton Health Access Initiative (CHAI) and the Global Fund. Laurus Labs holds WHO-Prequalification, USFDA, EU-GMP, and TGA regulatory approvals, and is a key manufacturing partner supporting India’s National AIDS Control Programme (NACP). The company’s ART formulations are among the most widely dispensed antiretroviral medicines in India and internationally.

Additional Details

Brand Name: Trilavir D Tablet

Generic Composition: Lamivudine 150mg + Zidovudine 300mg + Nevirapine 200mg

Drug Class: NRTI + NNRTI Fixed-Dose Combination (FDC)

Therapeutic Use: HIV-1 infection treatment as part of combination ART

Dosage Form: Film-coated oral tablet

Pack Size: Bottle of 30 tablets

Manufacturer: Laurus Labs Limited, Hyderabad, India

Prescription Status: Prescription required (Schedule H)

Storage: Store at 15–30°C in a cool, dry place away from moisture and direct sunlight

Country of Origin: India

Customer Reviews

4.0

★★★★☆

3 reviews

5 ★

4 ★

3 ★

2 ★

1 ★

Ankit R.

★★★★★

12 June 2026

Doctor recommended Trilavir-D as part of my treatment. I checked the medicine information before ordering and everything was easy to understand. Overall good experience.

Deepak M.

★★★★☆

29 January 2026

First time ordering Trilavir-D Tablet. Information on the page was helpful and process was simple. Overall satisfied with the experience.

Harsh V.

★★★☆☆

16 September 2025

Overall okay experience. I wanted to know more about the medicine before ordering and the details available helped me. Process was smooth.

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Recommended Lab Tests

CD4 Count Test: Measures immune function and disease progression.

HIV Viral Load Test: Determines the level of HIV in the bloodstream.

Liver Function Test (LFT): Monitors liver health during treatment.

Complete Blood Count (CBC): Checks for anemia and blood disorders.

Kidney Function Test (KFT): Ensures the kidneys are functioning properly.

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Trilavir D ART Tablet

Uses & Benefits

How it works?

NRTI Action — Lamivudine & Zidovudine

NNRTI Action — Nevirapine

Combined Viral Suppression

How to take?

Safety Advice

Alcohol

Pregnancy

Breastfeeding

Driving

Kidney

Liver

Side Effects

⚡ Common Side Effects

⚠️ Serious – Seek Help Immediately

Frequently Asked Questions

What is Trilavir D Tablet used for?

What is the composition of Trilavir D Tablet?

How does Trilavir D Tablet work to treat HIV?

What is the recommended dosage of Trilavir D Tablet?

Can Trilavir D Tablet cure HIV or AIDS?

What are the common and serious side effects of Trilavir D Tablet?

Does Trilavir D Tablet interact with other medicines?

Is Trilavir D Tablet safe during pregnancy or breastfeeding?

What tests are needed before and during Trilavir D Tablet treatment?

Who should not take Trilavir D Tablet?

Manufacturer

Additional Details

Customer Reviews

Recommended Lab Tests

Other Alternative Medicines

Storage Instructions

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