Description
Generic Name:
Dolutegravir, Lamivudine, Tenofovir Disoproxil Fumarate
Composition:
Each Viropil Tablet contains:
- Dolutegravir 50 mg
- Lamivudine 300 mg
- Tenofovir Disoproxil Fumarate 300 mg
Indication:
Viropil Tablet is indicated for the treatment of HIV-1 infection in adults and adolescents. It is also used as Post-Exposure Prophylaxis (PEP) to reduce the risk of HIV infection after potential exposure.
Storage Instructions:
- Store at 15°C to 30°C in a cool, dry place.
- Keep the medicine away from moisture and direct sunlight.
- Store in the original packaging to protect from contamination.
- Keep out of reach of children and pets.
Uses of the Medicine:
- Treatment of HIV-1 infection in adults and adolescents.
- Post-Exposure Prophylaxis (PEP) to prevent HIV infection after exposure to HIV.
Benefits of the Medicine:
- Effectively suppresses HIV viral load.
- Reduces the risk of HIV transmission after exposure.
- Supports immune system function by preventing virus replication.
- Convenient once-daily dosing improves adherence.
Side Effects:
Common side effects may include:
- Headache
- Nausea
- Fatigue
- Insomnia
- Diarrhea
Serious Side Effects Include:
- Lactic acidosis (muscle pain, rapid breathing, irregular heartbeat)
- Liver toxicity (yellowing of skin/eyes, dark urine)
- Hypersensitivity reactions (rash, fever, difficulty breathing)
- Kidney dysfunction (swelling, decreased urine output)
Seek immediate medical attention if you experience any of these serious side effects.
How to Use the Medicine:
- Take one tablet orally once daily with or without food.
- If used for PEP, start the medicine within 72 hours of exposure and continue for 28 days.
- Swallow the tablet whole with a glass of water.
- Follow your doctor’s instructions carefully.
How the Medicine Works:
Viropil Tablet contains a combination of three antiretroviral drugs:
- Dolutegravir: An integrase inhibitor that prevents HIV from integrating into human DNA.
- Lamivudine: A nucleoside reverse transcriptase inhibitor (NRTI) that blocks viral replication.
- Tenofovir Disoproxil Fumarate: Another NRTI that prevents the virus from multiplying.
Together, these drugs effectively block HIV replication and reduce the viral load.
What If You Forget to Take the Medicine?
- Take the missed dose as soon as you remember.
- If it is almost time for the next dose, skip the missed dose.
- Do not take a double dose to make up for the missed one.
Quick Tips:
- Start PEP as soon as possible—ideally within 72 hours of exposure.
- Always complete the full 28-day PEP regimen to maximize effectiveness.
- Regularly monitor your liver and kidney function during treatment.
- Use barrier protection (e.g., condoms) to prevent HIV and other STIs.
Safety Advice
Alcohol
Caution is advised when consuming alcohol with Viropil Tablet. Please consult your doctor for guidance.
Pregnancy
Viropil Tablet is unsafe to use during pregnancy due to potential harm to the developing baby. It may only be prescribed in life-threatening situations where benefits outweigh the risks. Please consult your doctor.
Breastfeeding
There is insufficient information on the use of Viropil Tablet while breastfeeding. Please consult your doctor before use.
Driving
It is uncertain whether Viropil Tablet affects your ability to drive. Avoid driving if you experience drowsiness, dizziness, or reduced alertness.
Kidney
Limited data is available on the safety of Viropil Tablet in patients with kidney disease. Dose adjustments may be necessary. Please consult your doctor.
Liver
Viropil Tablet should be used with caution in patients with liver disease. Dose adjustments may be required based on the severity of the condition. Please consult your doctor.
FAQs:
Q: Can Viropil Tablet cure HIV?
A: No, Viropil cannot cure HIV but effectively manages and controls the virus.
Q: Is Viropil effective as PEP?
A: Yes, it is used for Post-Exposure Prophylaxis to reduce the risk of HIV infection if taken within 72 hours of exposure.
Q: Can I take Viropil if I am pregnant?
A: Consult your healthcare provider if you are pregnant or planning to become pregnant.
Q: What should I do if I miss a dose?
A: Take it as soon as possible, but if it is close to your next dose, skip it. Do not double up on doses.
Related Lab Tests:
HIV test (before and after completing PEP)
Liver function test
Kidney function test
Viral load test (for HIV-positive individuals)
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