What is Spegra PEP Tablet used for?
›Spegra PEP Tablet is used as part of post-exposure prophylaxis after a possible recent exposure to HIV. It contains antiretroviral medicines that may help reduce the risk of HIV infection when started on time and taken exactly as prescribed. Spegra PEP should only be used after consultation with a qualified HIV doctor or healthcare provider.
When should Spegra PEP be started after HIV exposure?
›Spegra PEP should be started as soon as possible after possible HIV exposure, ideally within 24 hours and not later than 72 hours. PEP is considered an emergency prevention treatment, and every hour matters. A doctor will first assess the exposure risk before prescribing the right PEP medicine. CDC and NIH guidance states that PEP should be started within 72 hours and taken daily for 28 days if prescribed.
Is Spegra PEP a prescription medicine?
›Yes, Spegra PEP is a prescription-only medicine. It should not be taken without medical advice because the doctor needs to check your exposure history, HIV status, kidney/liver health, current medicines, pregnancy status if applicable, and possible drug interactions before starting PEP.
How long should I take Spegra PEP?
›PEP is usually taken once daily for 28 days, or as prescribed by your doctor. Do not stop the medicine early, even if you feel well. Completing the full prescribed course is important for best protection after possible HIV exposure. NIH HIVinfo also states that prescribed PEP medicines are taken every day for 28 days.
Can Spegra PEP guarantee 100% HIV prevention?
›No, Spegra PEP cannot guarantee 100% HIV prevention. PEP can significantly reduce the risk of HIV infection when started quickly and taken correctly, but it is not a guaranteed cure or complete protection. For best results, start PEP within the recommended time window, take every dose as advised, avoid further exposure, and complete follow-up HIV testing.
What tests are required before and after taking Spegra PEP?
›Before starting Spegra PEP, the doctor may recommend baseline HIV testing, kidney function test, liver function test, hepatitis B/C screening, and STI testing depending on the exposure type. Follow-up HIV testing is usually advised after completion of PEP and again later as per medical guidance. CDC's 2025 nPEP guidance includes follow-up care and HIV testing after exposure.
What are the common side effects of Spegra PEP?
›Common side effects may include nausea, headache, tiredness, dizziness, stomach upset, loose motions, or sleep disturbance. Most side effects are mild and improve with time, but you should contact your doctor if symptoms are severe, persistent, or if you develop rash, yellowing of eyes, breathing difficulty, or unusual weakness.
Can pregnant women take Spegra PEP?
›Pregnant women should not self-medicate with Spegra PEP, but PEP may be considered after possible HIV exposure under specialist medical supervision. The doctor will assess exposure risk, pregnancy stage, current health, and the safest suitable regimen. Current guidance on dolutegravir says first-trimester exposure has not been associated with increased risk of congenital anomalies, including neural tube defects, but treatment decisions during pregnancy must be doctor-guided.
What should I do if I miss a dose of Spegra PEP?
›If you miss a dose of Spegra PEP, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not take two doses together unless your doctor tells you to. Missing doses can reduce the effectiveness of PEP, so contact your doctor if you miss more than one dose.
What is the difference between PEP and PrEP?
›PEP is taken after a possible HIV exposure, while PrEP is taken before exposure by people who may have ongoing risk. PEP is an emergency 28-day course that should be started within 72 hours after exposure. PrEP is a planned prevention option for people with repeated or ongoing HIV exposure risk. CDC notes that people with frequent or recurrent exposure should be considered for PrEP after completing a 28-day PEP course if needed.
Can I buy Spegra PEP Tablet online without a prescription?
›No, Spegra PEP Tablet should not be purchased or used without a valid prescription. Since PEP is time-sensitive and depends on exposure risk, you should first consult an HIV doctor. The doctor will confirm whether PEP is needed and whether Spegra PEP is suitable for you.
Is Spegra PEP used for regular HIV treatment?
›Spegra PEP is used for post-exposure prophylaxis after possible HIV exposure, not as a replacement for long-term HIV treatment unless specifically prescribed by a doctor. If you are already diagnosed with HIV or need ongoing antiretroviral therapy, consult an HIV specialist for the correct ART regimen.