Description
Generic Name:
Taftrio Tablet contains Elexacaftor, Tezacaftor, Ivacaftor.
Composition:
Each Taftrio Tablet comprises:
- Elexacaftor (100 mg)
- Tezacaftor (50 mg)
- Ivacaftor (75 mg)
Indication:
Taftrio is indicated for the treatment of cystic fibrosis (CF) in patients 12 years and older with at least one F508del mutation in the CFTR gene.
Storage Instructions:
- Store at room temperature (25°C) in a dry place.
- Keep away from direct sunlight and moisture.
- Keep out of reach of children.
Uses of the Medicine:
- Improves lung function in patients with cystic fibrosis.
- Reduces the frequency of lung infections.
- Helps in improving breathing and overall respiratory health.
Benefits of the Medicine:
- Enhances the function of CFTR protein, improving mucus clearance in the lungs.
- Reduces exacerbations and hospitalizations.
- Improves nutritional absorption by enhancing digestive function.
- Enhances quality of life by reducing CF symptoms.
Side Effects:
- Common side effects include:
- Headache
- Nausea
- Diarrhea
- Fatigue
- Abdominal pain
- Increased liver enzymes
- Serious Side Effects Include:
- Liver toxicity (yellowing of skin/eyes, dark urine, loss of appetite)
- Breathing difficulties
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Blurred vision or eye problems
How to Use the Medicine:
- Take one tablet daily with a high-fat meal.
- Swallow whole with water; do not chew or crush.
- Do not skip doses to maintain effectiveness.
How the Medicine Works:
Taftrio is a CFTR modulator therapy that works by improving the function of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. It helps in restoring normal mucus flow and reducing lung infections in cystic fibrosis patients.
What If You Forget to Take the Medicine?
- Take the missed dose within 12 hours of the scheduled time.
- If more than 12 hours have passed, skip the missed dose.
- Do not take a double dose to make up for the missed one.
Quick Tips:
- Take Taftrio with fatty food to improve absorption.
- Regular liver function tests are recommended.
- Avoid grapefruit and Seville oranges, as they may affect drug metabolism.
- Inform your doctor if you have a history of liver disease.
Safety Advice
Alcohol
Caution is advised when consuming alcohol with Taftrio Tablet. Please consult your doctor for guidance.
Pregnancy
Taftrio Tablet is unsafe to use during pregnancy due to potential harm to the developing baby. It may only be prescribed in life-threatening situations where benefits outweigh the risks. Please consult your doctor.
Breastfeeding
There is insufficient information on the use of Taftrio Tablet while breastfeeding. Please consult your doctor before use.
Driving
It is uncertain whether Taftrio Tablet affects your ability to drive. Avoid driving if you experience drowsiness, dizziness, or reduced alertness.
Kidney
Limited data is available on the safety of Taftrio Tablet in patients with kidney disease. Dose adjustments may be necessary. Please consult your doctor.
Liver
Taftrio Tablet should be used with caution in patients with liver disease. Dose adjustments may be required based on the severity of the condition. Please consult your doctor.
FAQs:
Q: Can Taftrio cure cystic fibrosis?
A: No, Taftrio does not cure CF but helps manage symptoms and improve quality of life.
Q: Can I stop taking Taftrio if I feel better?
A: No, stopping Taftrio may cause symptoms to worsen. Always follow your doctor’s guidance.
Q: Can Taftrio be taken with other CF medications?
A: Yes, but inform your doctor about all medications you are taking to avoid interactions.
Related Lab Tests:
- Liver function test
- Spirometry (lung function test)
- Sweat chloride test
- Complete blood count (CBC)
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